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Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction

Mutations in the Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene are linked to Fragile X Syndrome, the most common monogenic cause of intellectual disability and autism. People affected with mutations in FMR1 have higher incidence of obesity, but the mechanisms are largely unknown. In the curren...

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Detalles Bibliográficos
Autores principales: Ruggiero-Ruff, Rebecca E., Villa, Pedro A., Hijleh, Sarah Abu, Avalos, Bryant, DiPatrizio, Nicholas V., Haga-Yamanaka, Sachiko, Coss, Djurdjica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403586/
https://www.ncbi.nlm.nih.gov/pubmed/37542065
http://dx.doi.org/10.1038/s41598-023-39643-z