Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies

Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human application requires detailed knowledge of its interaction...

Descripción completa

Detalles Bibliográficos
Autores principales: Penner, Inessa, Dejung, Mario, Freiwald, Anja, Butter, Falk, Chen, Jia-Xuan, Plachter, Bodo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403606/
https://www.ncbi.nlm.nih.gov/pubmed/37542058
http://dx.doi.org/10.1038/s41597-023-02418-2
_version_ 1785085106708283392
author Penner, Inessa
Dejung, Mario
Freiwald, Anja
Butter, Falk
Chen, Jia-Xuan
Plachter, Bodo
author_facet Penner, Inessa
Dejung, Mario
Freiwald, Anja
Butter, Falk
Chen, Jia-Xuan
Plachter, Bodo
author_sort Penner, Inessa
collection PubMed
description Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human application requires detailed knowledge of its interaction with the host. A comprehensive mass spectrometry (MS)- based analysis was performed regarding the changes in the proteome of cell culture cells, exposed to DB.
format Online
Article
Text
id pubmed-10403606
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-104036062023-08-06 Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies Penner, Inessa Dejung, Mario Freiwald, Anja Butter, Falk Chen, Jia-Xuan Plachter, Bodo Sci Data Data Descriptor Human cytomegalovirus (HCMV) is a pathogen of high medical relevance. Subviral Dense Bodies (DB) were developed as a vaccine candidate to ameliorate the severe consequences of HCMV infection. Development of such a candidate vaccine for human application requires detailed knowledge of its interaction with the host. A comprehensive mass spectrometry (MS)- based analysis was performed regarding the changes in the proteome of cell culture cells, exposed to DB. Nature Publishing Group UK 2023-08-04 /pmc/articles/PMC10403606/ /pubmed/37542058 http://dx.doi.org/10.1038/s41597-023-02418-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Penner, Inessa
Dejung, Mario
Freiwald, Anja
Butter, Falk
Chen, Jia-Xuan
Plachter, Bodo
Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title_full Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title_fullStr Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title_full_unstemmed Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title_short Proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral Dense Bodies
title_sort proteome changes of fibroblasts and endothelial cells upon incubation with human cytomegalovirus subviral dense bodies
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403606/
https://www.ncbi.nlm.nih.gov/pubmed/37542058
http://dx.doi.org/10.1038/s41597-023-02418-2
work_keys_str_mv AT pennerinessa proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies
AT dejungmario proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies
AT freiwaldanja proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies
AT butterfalk proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies
AT chenjiaxuan proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies
AT plachterbodo proteomechangesoffibroblastsandendothelialcellsuponincubationwithhumancytomegalovirussubviraldensebodies

Ejemplares similares