Transient anti-cytokine autoantibodies superimpose the hyperinflammatory response in Kawasaki disease and multisystem inflammatory syndrome in children: a comparative cohort study on correlates of disease

BACKGROUND: Children with SARS-CoV-2 related Multisystem Inflammatory Syndrome in Children (MIS-C) often present with clinical features that resemble Kawasaki disease (KD). Disease severity in adult COVID-19 is associated to the presence of anti-cytokine autoantibodies (ACAAs) against type I interfe...

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Autores principales: Netea, Stejara A., Biesbroek, Giske, van Stijn, Diana, Ijspeert, Hanna, van der Made, Caspar I., Jansen, Machiel H., Geissler, Judy, van den Berg, J.M. (Merlijn), van der Kuip, Martijn, Gruppen, Mariken P., Schonenberg-Meinema, Dieneke, Kapitein, Berber, van Furth, A.M. (Marceline) Tutu, Nagelkerke, Sietse Q., Pajkrt, Dasja, Plötz, Frans B., den Boer, M.E.J. (Lisette), Landman, Gijs W., van Houten, Marlies A., Goetschalckx, Ines, Toonen, Erik J.M., van de Veerdonk, Frank L., Kuipers, Irene M., Dik, Willem A., Kuijpers, Taco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403726/
https://www.ncbi.nlm.nih.gov/pubmed/37524002
http://dx.doi.org/10.1016/j.ebiom.2023.104736

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