Protection of pancreatic islets from oxidative cell death by a peripherally-active morphinan with increased drug safety

OBJECTIVE: Dextromethorphan (DXM) is a commonly used antitussive medication with positive effects in people with type 2 diabetes mellitus, since it increases glucose tolerance and protects pancreatic islets from cell death. However, its use as an antidiabetic medication is limited due to its central...

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Detalles Bibliográficos
Autores principales: Scholz, Okka, Huß, Elena, Otter, Silke, Herebian, Diran, Hamacher, Anna, Levy, Laura Mariana, Hristeva, Stanimira, Sanz, Miguel, Ajani, Haresh, Puentes, Alfredo Rodriguez, Hoffmann, Torsten, Hogeback, Jens, Unger, Anke, Terheyden, Susanne, Reina do Fundo, Michelle, Dewidar, Bedair, Roden, Michael, Lammert, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403733/
https://www.ncbi.nlm.nih.gov/pubmed/37451343
http://dx.doi.org/10.1016/j.molmet.2023.101775

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