Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration

Microglia are the resident innate immune cells in the brain with a major role in orchestrating immune responses. They also provide a frontline of host defense in the central nervous system (CNS) through their active phagocytic capability. Being a professional phagocyte, microglia participate in phag...

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Detalles Bibliográficos
Autores principales: Quick, Joseph D., Silva, Cristian, Wong, Jia Hui, Lim, Kah Leong, Reynolds, Richard, Barron, Anna M., Zeng, Jialiu, Lo, Chih Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403868/
https://www.ncbi.nlm.nih.gov/pubmed/37543564
http://dx.doi.org/10.1186/s12974-023-02866-y

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