RNA-binding protein CCDC137 activates AKT signaling and promotes hepatocellular carcinoma through a novel non-canonical role of DGCR8 in mRNA localization

BACKGROUND: RNA binding proteins (RBPs)—regulated gene expression play a vital role in various pathological processes, including the progression of cancer. However, the role of RBP in hepatocellular carcinoma (HCC) remains much unknown. In this study, we aimed to explore the contribution of RBP CCDC...

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Detalles Bibliográficos
Autores principales: Tao, Shuang, Xie, Shu-Juan, Diao, Li-Ting, Lv, Guo, Hou, Ya-Rui, Hu, Yan-Xia, Xu, Wan-Yi, Du, Bin, Xiao, Zhen-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403887/
https://www.ncbi.nlm.nih.gov/pubmed/37542342
http://dx.doi.org/10.1186/s13046-023-02749-3

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