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Optimized bisulfite sequencing analysis reveals the lack of 5-methylcytosine in mammalian mitochondrial DNA
BACKGROUND: DNA methylation is one of the best characterized epigenetic modifications in the mammalian nuclear genome and is known to play a significant role in various biological processes. Nonetheless, the presence of 5-methylcytosine (5mC) in mitochondrial DNA remains controversial, as data rangi...
Autores principales: | Shao, Zhenyu, Han, Yang, Zhou, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403921/ https://www.ncbi.nlm.nih.gov/pubmed/37542258 http://dx.doi.org/10.1186/s12864-023-09541-9 |
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