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The interwoven fibril-like structure of amyloid-beta plaques in mouse brain tissue visualized using super-resolution STED microscopy

BACKGROUND: Standard neuropathologic analysis of Alzheimer’s brain relies on traditional fluorescence microscopy, which suffers from limited spatial resolution due to light diffraction. As a result, it fails to reveal intricate details of amyloid plaques. While electron microscopy (EM) offers higher...

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Detalles Bibliográficos
Autores principales: Johansson, Björn, Oasa, Sho, Muntsant Soria, Aida, Tiiman, Ann, Söderberg, Linda, Amandius, Ebba, Möller, Christer, Lannfelt, Lars, Terenius, Lars, Giménez-Llort, Lydia, Vukojević, Vladana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403925/
https://www.ncbi.nlm.nih.gov/pubmed/37542303
http://dx.doi.org/10.1186/s13578-023-01086-4