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A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis
A 70-year-old man, a known case of diabetes mellitus since 10 years ago, presented with lower limb swelling and dyspnea on exertion for one month and dysphagia to solids associated with early satiety for 2 weeks. The patient had palmoplantar keratosis (PPK), which was present since birth with a simi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Iranian Association of Gastroerterology and Hepatology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404083/ https://www.ncbi.nlm.nih.gov/pubmed/37546510 http://dx.doi.org/10.34172/mejdd.2023.335 |
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author | Vincent Comraj, Delvina Zainab, Ayisha Arthur, Manisha Chauhan, Jaba Pandurangan, Viswanathan Srinivasan, Devasena |
author_facet | Vincent Comraj, Delvina Zainab, Ayisha Arthur, Manisha Chauhan, Jaba Pandurangan, Viswanathan Srinivasan, Devasena |
author_sort | Vincent Comraj, Delvina |
collection | PubMed |
description | A 70-year-old man, a known case of diabetes mellitus since 10 years ago, presented with lower limb swelling and dyspnea on exertion for one month and dysphagia to solids associated with early satiety for 2 weeks. The patient had palmoplantar keratosis (PPK), which was present since birth with a similar family history. The patient was admitted to rule out esophageal malignancy. Upper gastrointestinal gastroscopy revealed esophagitis and esophageal melanosis with gastric mucosal erythema. Biopsies samples were taken. Histopathological examination revealed reflux esophagitis and chronic active Helicobacter pylori gastritis with no evidence of malignancy. His symptoms improved following H. pylori eradication and treatment for coronary artery disease and heart failure. The patient was advised of regular follow-up as he had risk factors for the development of esophageal melanoma or squamous cell carcinoma. |
format | Online Article Text |
id | pubmed-10404083 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Iranian Association of Gastroerterology and Hepatology |
record_format | MEDLINE/PubMed |
spelling | pubmed-104040832023-08-06 A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis Vincent Comraj, Delvina Zainab, Ayisha Arthur, Manisha Chauhan, Jaba Pandurangan, Viswanathan Srinivasan, Devasena Middle East J Dig Dis Case Report A 70-year-old man, a known case of diabetes mellitus since 10 years ago, presented with lower limb swelling and dyspnea on exertion for one month and dysphagia to solids associated with early satiety for 2 weeks. The patient had palmoplantar keratosis (PPK), which was present since birth with a similar family history. The patient was admitted to rule out esophageal malignancy. Upper gastrointestinal gastroscopy revealed esophagitis and esophageal melanosis with gastric mucosal erythema. Biopsies samples were taken. Histopathological examination revealed reflux esophagitis and chronic active Helicobacter pylori gastritis with no evidence of malignancy. His symptoms improved following H. pylori eradication and treatment for coronary artery disease and heart failure. The patient was advised of regular follow-up as he had risk factors for the development of esophageal melanoma or squamous cell carcinoma. Iranian Association of Gastroerterology and Hepatology 2023-04 2023-04-30 /pmc/articles/PMC10404083/ /pubmed/37546510 http://dx.doi.org/10.34172/mejdd.2023.335 Text en © 2023 Middle East Journal of Digestive Diseases https://creativecommons.org/licenses/by-nc/4.0/This work is published by Middle East Journal of Digestive Diseases as an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). Non-commercial uses of the work are permitted, provided the original work is properly cited. |
spellingShingle | Case Report Vincent Comraj, Delvina Zainab, Ayisha Arthur, Manisha Chauhan, Jaba Pandurangan, Viswanathan Srinivasan, Devasena A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title | A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title_full | A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title_fullStr | A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title_full_unstemmed | A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title_short | A Case Report of Hereditary Palmoplantar Keratoderma with Esophageal Melanosis |
title_sort | case report of hereditary palmoplantar keratoderma with esophageal melanosis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404083/ https://www.ncbi.nlm.nih.gov/pubmed/37546510 http://dx.doi.org/10.34172/mejdd.2023.335 |
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