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Parry Romberg Syndrome: A Case Report and an Insight Into Etiology

Parry-Romberg syndrome (PRS) is a rare degenerative disorder of unknown cause that causes slow, progressive atrophy on one side of the face. The cause may be a malfunction of the sympathetic nervous system, with or without neurological symptoms. Atrophy usually begins in childhood and progresses gra...

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Autores principales: Kumar, Munish, Singla, Robin, Singh, Gagandeep, Kasrija, Rishabh, Sharma, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404130/
https://www.ncbi.nlm.nih.gov/pubmed/37546075
http://dx.doi.org/10.7759/cureus.41465
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author Kumar, Munish
Singla, Robin
Singh, Gagandeep
Kasrija, Rishabh
Sharma, Manish
author_facet Kumar, Munish
Singla, Robin
Singh, Gagandeep
Kasrija, Rishabh
Sharma, Manish
author_sort Kumar, Munish
collection PubMed
description Parry-Romberg syndrome (PRS) is a rare degenerative disorder of unknown cause that causes slow, progressive atrophy on one side of the face. The cause may be a malfunction of the sympathetic nervous system, with or without neurological symptoms. Atrophy usually begins in childhood and progresses gradually over several years. Stabilization can take up to 20 years. There is no definitive cure for this condition, but once the condition is stabilized, reconstructive surgery of the damaged skin and soft tissue can correct the deformity. The objective of this article is to present an insight into the etiology of PRS with a case report of a 15-year-old male patient, who was diagnosed with PRS due to trauma and developed progressive hemifacial atrophy without neurological manifestations. PRS is a progressive disease that severely affects one side of the face. Because of its devastating effects on the entire body, treatment requires a multidisciplinary approach. Further research is needed to clearly understand the etiology and provide patients with accurate treatment plans.
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spelling pubmed-104041302023-08-06 Parry Romberg Syndrome: A Case Report and an Insight Into Etiology Kumar, Munish Singla, Robin Singh, Gagandeep Kasrija, Rishabh Sharma, Manish Cureus Pathology Parry-Romberg syndrome (PRS) is a rare degenerative disorder of unknown cause that causes slow, progressive atrophy on one side of the face. The cause may be a malfunction of the sympathetic nervous system, with or without neurological symptoms. Atrophy usually begins in childhood and progresses gradually over several years. Stabilization can take up to 20 years. There is no definitive cure for this condition, but once the condition is stabilized, reconstructive surgery of the damaged skin and soft tissue can correct the deformity. The objective of this article is to present an insight into the etiology of PRS with a case report of a 15-year-old male patient, who was diagnosed with PRS due to trauma and developed progressive hemifacial atrophy without neurological manifestations. PRS is a progressive disease that severely affects one side of the face. Because of its devastating effects on the entire body, treatment requires a multidisciplinary approach. Further research is needed to clearly understand the etiology and provide patients with accurate treatment plans. Cureus 2023-07-06 /pmc/articles/PMC10404130/ /pubmed/37546075 http://dx.doi.org/10.7759/cureus.41465 Text en Copyright © 2023, Kumar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Kumar, Munish
Singla, Robin
Singh, Gagandeep
Kasrija, Rishabh
Sharma, Manish
Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title_full Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title_fullStr Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title_full_unstemmed Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title_short Parry Romberg Syndrome: A Case Report and an Insight Into Etiology
title_sort parry romberg syndrome: a case report and an insight into etiology
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404130/
https://www.ncbi.nlm.nih.gov/pubmed/37546075
http://dx.doi.org/10.7759/cureus.41465
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