Applicability of the DPRA on mixture testing: challenges and opportunities

The in chemico direct peptide reactivity assay (DPRA) is validated to assess protein reactivity of chemical compounds, relating to the molecular initiating event of skin sensitization induction. According to OECD TG 442C, the DPRA is technically applicable to test multi-constituent substances and mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Marcelis, Quinten, Deconinck, Eric, Rogiers, Vera, Vanhaecke, Tamara, Desmedt, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Immunotoxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404183/
https://www.ncbi.nlm.nih.gov/pubmed/37414884
http://dx.doi.org/10.1007/s00204-023-03551-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404183/
https://www.ncbi.nlm.nih.gov/pubmed/37414884
http://dx.doi.org/10.1007/s00204-023-03551-y

Ejemplares similares