The ubiquitin ligase TRIM32 promotes the autophagic response to Mycobacterium tuberculosis infection in macrophages

Mycobacterium tuberculosis (Mtb) is known to evade host immune responses and persist in macrophages for long periods. A mechanism that the host uses to combat Mtb is xenophagy, a selective form of autophagy that targets intracellular pathogens for degradation. Ubiquitination of Mtb or Mtb-containing...

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Detalles Bibliográficos
Autores principales: Romagnoli, Alessandra, Di Rienzo, Martina, Petruccioli, Elisa, Fusco, Carmela, Palucci, Ivana, Micale, Lucia, Mazza, Tommaso, Delogu, Giovanni, Merla, Giuseppe, Goletti, Delia, Piacentini, Mauro, Fimia, Gian Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404268/
https://www.ncbi.nlm.nih.gov/pubmed/37543647
http://dx.doi.org/10.1038/s41419-023-06026-1

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