Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report

Primary central nervous system (CNS) lymphoma or systemic non-Hodgkin lymphoma that infiltrates the CNS can cause central diabetes insipidus (CDI). Polyuria and polydipsia should raise the suspicion of CDI development in patients with lymphoma that infiltrates the CNS. CDI is effectively treated wit...

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Detalles Bibliográficos
Autores principales: Koumpis, Epameinondas, Kyriazopoulou, Lydia, Tigas, Stelios, Kapsali, Eleni, Hatzimichael, Eleftheria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404345/
https://www.ncbi.nlm.nih.gov/pubmed/37551214
http://dx.doi.org/10.7759/cureus.41500
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author Koumpis, Epameinondas
Kyriazopoulou, Lydia
Tigas, Stelios
Kapsali, Eleni
Hatzimichael, Eleftheria
author_facet Koumpis, Epameinondas
Kyriazopoulou, Lydia
Tigas, Stelios
Kapsali, Eleni
Hatzimichael, Eleftheria
author_sort Koumpis, Epameinondas
collection PubMed
description Primary central nervous system (CNS) lymphoma or systemic non-Hodgkin lymphoma that infiltrates the CNS can cause central diabetes insipidus (CDI). Polyuria and polydipsia should raise the suspicion of CDI development in patients with lymphoma that infiltrates the CNS. CDI is effectively treated with desmopressin. However, careful monitoring of the patient's serum sodium, fluid intake, urine output, and weight is necessary because patients receiving desmopressin may develop hyponatremia, so they should be alert to recognize this side effect promptly. Moreover, CDI due to lymphoma can occasionally be reversible. Therefore, the dosage of desmopressin should be adapted during or after the treatment of lymphoma.
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spelling pubmed-104043452023-08-07 Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report Koumpis, Epameinondas Kyriazopoulou, Lydia Tigas, Stelios Kapsali, Eleni Hatzimichael, Eleftheria Cureus Endocrinology/Diabetes/Metabolism Primary central nervous system (CNS) lymphoma or systemic non-Hodgkin lymphoma that infiltrates the CNS can cause central diabetes insipidus (CDI). Polyuria and polydipsia should raise the suspicion of CDI development in patients with lymphoma that infiltrates the CNS. CDI is effectively treated with desmopressin. However, careful monitoring of the patient's serum sodium, fluid intake, urine output, and weight is necessary because patients receiving desmopressin may develop hyponatremia, so they should be alert to recognize this side effect promptly. Moreover, CDI due to lymphoma can occasionally be reversible. Therefore, the dosage of desmopressin should be adapted during or after the treatment of lymphoma. Cureus 2023-07-07 /pmc/articles/PMC10404345/ /pubmed/37551214 http://dx.doi.org/10.7759/cureus.41500 Text en Copyright © 2023, Koumpis et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Koumpis, Epameinondas
Kyriazopoulou, Lydia
Tigas, Stelios
Kapsali, Eleni
Hatzimichael, Eleftheria
Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title_full Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title_fullStr Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title_full_unstemmed Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title_short Central Diabetes Insipidus in a Patient With Lymphoma: A Case Report
title_sort central diabetes insipidus in a patient with lymphoma: a case report
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404345/
https://www.ncbi.nlm.nih.gov/pubmed/37551214
http://dx.doi.org/10.7759/cureus.41500
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