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Swertiamarin or heat-transformed products alleviated APAP-induced hepatotoxicity via modulation of apoptotic and Nrf-2/NF-κB pathways

OBJECTIVE: Swertiamarin (STM) belongs to iridoid class of compounds, and the heat-transformed products (HTPS) are produced by STM in the process of drug processing. The purpose of this study was to explore the protective effect and mechanism of STM or HTPS on acetaminophen (APAP)-induced hepatotoxic...

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Detalles Bibliográficos
Autores principales:	Zhou, Qian, Zhou, Qixiu, Xia, Rui, Zhang, Peng, Xie, Yanqing, Yang, Zhuya, Khan, Afsar, Zhou, Zhihong, Tan, Wenhong, Liu, Lu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404768/ https://www.ncbi.nlm.nih.gov/pubmed/37554797 http://dx.doi.org/10.1016/j.heliyon.2023.e18746

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