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Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation

The transcription factor retinoic acid–related orphan receptor α (RORα) is important in regulating several physiological functions, such as cellular development, circadian rhythm, metabolism, and immunity. In two in vivo animal models of type 2 lung inflammation, Nippostrongylus brasiliensis infecti...

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Detalles Bibliográficos
Autores principales: Roberts, Joseph, Chevalier, Anne, Hawerkamp, Heike C., Yeow, Aoife, Matarazzo, Laura, Schwartz, Christian, Hams, Emily, Fallon, Padraic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10404816/
https://www.ncbi.nlm.nih.gov/pubmed/37387671
http://dx.doi.org/10.4049/jimmunol.2200896

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