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Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment

Weight gain is a common harmful side effect of atypical antipsychotics used for schizophrenia treatment. Conversely, treatment with the novel phosphodiesterase-10A (PDE10A) inhibitor MK-8189 in clinical trials led to significant weight reduction, especially in patients with obesity. This study aimed...

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Detalles Bibliográficos
Autores principales:	Tomaszewski, Michal R., Meng, Xiangjun, Haley, Hyking D., Harrell, Charles M., Mcdonald, Terrence P., Miller, Corin O., Smith, Sean M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405059/ https://www.ncbi.nlm.nih.gov/pubmed/37393952 http://dx.doi.org/10.1016/j.jlr.2023.100408

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