Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection

Individuals with Down syndrome (DS) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how DS influences homeostatic physiology of lung airway, and its reactive responses to pulmonary pathogens. We generated well-differentiated ciliated airway epithelia using tr...

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Detalles Bibliográficos
Autores principales: Thomas, Samantha N., Niemeyer, Brian F., Jimenez-Valdes, Rocio J., Kaiser, Alexander J., Espinosa, Joaquin M., Sullivan, Kelly D., Goodspeed, Andrew, Costello, James C., Alder, Jonathan K., Cañas-Arranz, Rodrigo, García-Sastre, Adolfo, Benam, Kambez H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405068/
https://www.ncbi.nlm.nih.gov/pubmed/37554445
http://dx.doi.org/10.1016/j.isci.2023.107361

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