Cargando…

Enhancer in cancer pathogenesis and treatment

Enhancers are essential cis-acting regulatory elements that determine cell identity and tumor progression. Enhancer function is dependent on the physical interaction between the enhancer and its target promoter inside its local chromatin environment. Enhancer reprogramming is an important mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Zhuo, Fan, Jinbo, Dang, Yixiong, Zhao, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2023
Materias:	Human and Medical Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405138/ https://www.ncbi.nlm.nih.gov/pubmed/37548349 http://dx.doi.org/10.1590/1678-4685-GMB-2022-0313

Ejemplares similares

Polymorphism of the catechol-O-methyltransferase gene in Han Chinese patients with psoriasis vulgaris
por: Gao, Lin, et al.
Publicado: (2009)

Identification of super-enhancer-associated transcription factors regulating glucose metabolism in poorly differentiated thyroid carcinoma
por: Liu, Kun, et al.
Publicado: (2022)

Enhanced levels of the apoptotic BAX/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features
por: Kaparou, Maria, et al.
Publicado: (2013)

RNAi-mediated silencing of the Bmi-1 gene causes growth inhibition and enhances doxorubicin-induced apoptosis in MCF-7 cells
por: Wu, Xiang-mei, et al.
Publicado: (2009)

Methylation in the promoter regions of WT1, NKX6-1 and DBC1 genes in cervical cancer tissues of Uygur women in Xinjiang
por: Wu, Dan, et al.
Publicado: (2018)

Breast cancer-associated SNP rs72755295 is a cis-regulatory variation for human EXO1
por: Shi, Qiang, et al.
Publicado: (2022)

Predicting the progress of colon cancer by DNA methylation markers of the p16 gene in feces - Evidence from an animal model
por: Wu, Wen-Chih, et al.
Publicado: (2013)

CYP3A5 genotyping for assessing the efficacy of treatment with simvastatin and atorvastatin
por: Kolovou, Genovefa, et al.
Publicado: (2015)

Cancer-related worry and risk perception in Brazilian individuals seeking genetic counseling for hereditary breast cancer
por: Palmero, Edenir Inêz, et al.
Publicado: (2020)

Polymorphisms associated with the risk of lung cancer in a healthy Mexican Mestizo population: Application of the additive model for cancer
por: Pérez-Morales, Rebeca, et al.
Publicado: (2011)

Long noncoding RNA POU6F2-AS1 regulates lung cancer aggressiveness through sponging miR-34c-5p to modulate KCNJ4 expression
por: Wu, Xiao-Yan, et al.
Publicado: (2021)

Population prevalence of hereditary breast cancer phenotypes and implementation of a genetic cancer risk assessment program in southern Brazil
por: Palmero, Edenir I., et al.
Publicado: (2009)

TSC1 and TSC2 gene mutations and their implications for treatment in Tuberous Sclerosis Complex: a review
por: Rosset, Clévia, et al.
Publicado: (2017)

Resveratrol effects in bladder cancer: A mini review
por: Almeida, Tamires Cunha, et al.
Publicado: (2021)

Estimating genomic instability mediated by Alu retroelements in breast cancer
por: Fazza, Ana Cristina, et al.
Publicado: (2009)

Absence of TERT promoter mutations in colorectal precursor lesions and cancer
por: Cruvinel-Carloni, Adriana, et al.
Publicado: (2018)

Novel mutations in breast cancer patients from southwestern Colombia
por: Solarte, Melissa, et al.
Publicado: (2020)

Differential gene expression profiles in peripheral blood in Northeast Chinese Han people with acute myocardial infarction
por: Fan, Lin, et al.
Publicado: (2018)

Polymorphisms of arylamine N-acetyltransferase2 and risk of lung and colorectal cancer
por: Mahasneh, Amjad, et al.
Publicado: (2012)

Association between HPV infection and prostate cancer in a Mexican population
por: Medel-Flores, Olivia, et al.
Publicado: (2018)

Correlation between vaginal microbiota and different progression stages of cervical cancer
por: Wei, Bing, et al.
Publicado: (2022)

Identification of novel mutations of Insulin Receptor Substrate 1 (IRS1) in tumor samples of non-small cell lung cancer (NSCLC): Implications for aberrant insulin signaling in development of cancer
por: Gorgisen, Gokhan, et al.
Publicado: (2019)

Engineered scPDL1-DM1 drug conjugate with improved in vitro analysis to target PD-L1 positive cancer cells and intracellular trafficking studies in cancer therapy
por: Kalim, Muhammad, et al.
Publicado: (2020)

Does the expression of the ACVR2A gene affect the development of colorectal cancer?
por: Wodziński, Damian, et al.
Publicado: (2019)

Differential admixture in Latin American populations and its impact on the study of colorectal cancer
por: Colistro, Valentina, et al.
Publicado: (2020)

Plasma GBP2 promoter methylation is associated with advanced stages in breast cancer
por: Rahvar, Farzaneh, et al.
Publicado: (2020)

TMEM147 is a novel biomarker for diagnosis and prognosis of hepatocellular carcinoma
por: Fan, Wen-Jie, et al.
Publicado: (2023)

Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges
por: Arshad, Sundas, et al.
Publicado: (2020)

Association between folate metabolism polymorphisms and breast cancer: a case-control study
por: Gimenez-Martins, Ana Paula D’Alarme, et al.
Publicado: (2021)

Expression of miR-148b-3p is correlated with overexpression of biomarkers in prostate cancer
por: Arámbula-Meraz, Eliakym, et al.
Publicado: (2020)

Resistance mutations of NS3 and NS5b in treatment-naïve patients infected with hepatitis C virus in Santa Catarina and Rio Grande do Sul states, Brazil
por: Andrade, Elisabete, et al.
Publicado: (2020)

A meta-analysis of ABCG2 gene polymorphism and non-small cell lung cancer outcomes
por: Fu, Lei, et al.
Publicado: (2020)

Systematic analyses of a novel circRNA-related miRNAs prognostic signature for Cervical Cancer
por: Wang, Shasha, et al.
Publicado: (2022)

DNA repair genes XRCC1 and XRCC3 polymorphisms and their relationship with the level of micronuclei in breast cancer patients
por: Santos, Raquel A., et al.
Publicado: (2010)

Transcriptional profile of fibroblasts obtained from the primary site, lymph node and bone marrow of breast cancer patients
por: Del Valle, Paulo Roberto, et al.
Publicado: (2014)

Contribution of DNA repair xeroderma pigmentosum group D genotypes to pancreatic cancer risk in the Chinese Han population
por: Yan, Dong, et al.
Publicado: (2017)

Association of polymorphisms of PTEN, AKT1, PI3K, AR, and AMACR genes in patients with prostate cancer
por: de Nóbrega, Monyse, et al.
Publicado: (2020)

Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer
por: Gomig, Talita Helen Bombardelli, et al.
Publicado: (2021)

Simultaneous quantitative assessment of circulating cell-free mitochondrial and nuclear DNA by multiplex real-time PCR
por: Xia, Peng, et al.
Publicado: (2009)

CYP1A1 genotypes and haplotypes and risk of oral cancer: A case-control study in South Indians
por: Balaji, Lakshmi, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qt8gs2aqae7g6q5ehr36dl4t81