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Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation
BACKGROUND: Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°–180°). Herein, we present our...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405331/ https://www.ncbi.nlm.nih.gov/pubmed/37554706 http://dx.doi.org/10.21037/acs-2023-avs2-18 |
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author | Kelly, John J. Desai, Nimesh D. Patrick, William L. Cannon, Brittany J. Zhao, Yu Mosbahi, Selim Berezowksi, Mikolaj Iyengar, Amit Szeto, Wilson Y. Bavaria, Joseph E. |
author_facet | Kelly, John J. Desai, Nimesh D. Patrick, William L. Cannon, Brittany J. Zhao, Yu Mosbahi, Selim Berezowksi, Mikolaj Iyengar, Amit Szeto, Wilson Y. Bavaria, Joseph E. |
author_sort | Kelly, John J. |
collection | PubMed |
description | BACKGROUND: Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°–180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°–150° orientation. METHODS: A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°–150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival. RESULTS: The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0–17.2%), 7.1% (0–19.7%), and 5.3% (0.3–22%), respectively. There was no mortality for the entire duration of the study period. CONCLUSIONS: This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required. |
format | Online Article Text |
id | pubmed-10405331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-104053312023-08-08 Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation Kelly, John J. Desai, Nimesh D. Patrick, William L. Cannon, Brittany J. Zhao, Yu Mosbahi, Selim Berezowksi, Mikolaj Iyengar, Amit Szeto, Wilson Y. Bavaria, Joseph E. Ann Cardiothorac Surg Featured Articles BACKGROUND: Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°–180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°–150° orientation. METHODS: A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°–150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival. RESULTS: The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0–17.2%), 7.1% (0–19.7%), and 5.3% (0.3–22%), respectively. There was no mortality for the entire duration of the study period. CONCLUSIONS: This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required. AME Publishing Company 2023-07-07 2023-07-31 /pmc/articles/PMC10405331/ /pubmed/37554706 http://dx.doi.org/10.21037/acs-2023-avs2-18 Text en 2023 Annals of Cardiothoracic Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Featured Articles Kelly, John J. Desai, Nimesh D. Patrick, William L. Cannon, Brittany J. Zhao, Yu Mosbahi, Selim Berezowksi, Mikolaj Iyengar, Amit Szeto, Wilson Y. Bavaria, Joseph E. Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title | Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title_full | Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title_fullStr | Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title_full_unstemmed | Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title_short | Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
title_sort | outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation |
topic | Featured Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405331/ https://www.ncbi.nlm.nih.gov/pubmed/37554706 http://dx.doi.org/10.21037/acs-2023-avs2-18 |
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