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Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report

BACKGROUND: Early myocardial calcifications secondary to fulminant myocarditis (FM) are rare, and their natural evolution and effects on cardiac function are poorly understood. Here, we followed the patient for 4 years to observe the development of cardiac calcification and its impact on heart funct...

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Autores principales: You, Binquan, Zeng, Congjun, Wang, Bingyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405352/
https://www.ncbi.nlm.nih.gov/pubmed/37554960
http://dx.doi.org/10.1093/ehjcr/ytad302
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author You, Binquan
Zeng, Congjun
Wang, Bingyin
author_facet You, Binquan
Zeng, Congjun
Wang, Bingyin
author_sort You, Binquan
collection PubMed
description BACKGROUND: Early myocardial calcifications secondary to fulminant myocarditis (FM) are rare, and their natural evolution and effects on cardiac function are poorly understood. Here, we followed the patient for 4 years to observe the development of cardiac calcification and its impact on heart function. CASE SUMMARY: A 16-year-old man was hospitalized with a fever and cough for 1 day. The patient was previously healthy and had no history of heart disease or specific family conditions. The patient was positive for anti-Epstein–Barr virus IgG and IgM. The computed tomography (CT) scan showed no coronary lesions. Cardiogenic shock and recurrent ventricular fibrillation developed on the third day after admission, and the patient received rescue therapy such as endotracheal intubation, defibrillation, extracorporeal membrane oxygenation, and corticosteroids. On the 13th day of admission, a CT scan revealed significant calcification in the left ventricular wall. The patient was discharged after 30 days in the hospital. After discharge, his left ventricular calcification peaked at 6 months and gradually subsided after that, and his left ventricular function slowly returned to normal at 12 months. DISCUSSION: In younger patients, myocardial calcifications secondary to FM may occur as early as 13 days and affect cardiac function. After proper treatment and rehabilitation, the patient’s myocardial calcification can gradually subside and the cardiac function can gradually recover. For FM patients, timely and comprehensive intensive treatment, including heart, lung, and kidney replacement therapy and early administration of hormone preparations, may be beneficial to the early recovery of patients.
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spelling pubmed-104053522023-08-08 Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report You, Binquan Zeng, Congjun Wang, Bingyin Eur Heart J Case Rep Case Report BACKGROUND: Early myocardial calcifications secondary to fulminant myocarditis (FM) are rare, and their natural evolution and effects on cardiac function are poorly understood. Here, we followed the patient for 4 years to observe the development of cardiac calcification and its impact on heart function. CASE SUMMARY: A 16-year-old man was hospitalized with a fever and cough for 1 day. The patient was previously healthy and had no history of heart disease or specific family conditions. The patient was positive for anti-Epstein–Barr virus IgG and IgM. The computed tomography (CT) scan showed no coronary lesions. Cardiogenic shock and recurrent ventricular fibrillation developed on the third day after admission, and the patient received rescue therapy such as endotracheal intubation, defibrillation, extracorporeal membrane oxygenation, and corticosteroids. On the 13th day of admission, a CT scan revealed significant calcification in the left ventricular wall. The patient was discharged after 30 days in the hospital. After discharge, his left ventricular calcification peaked at 6 months and gradually subsided after that, and his left ventricular function slowly returned to normal at 12 months. DISCUSSION: In younger patients, myocardial calcifications secondary to FM may occur as early as 13 days and affect cardiac function. After proper treatment and rehabilitation, the patient’s myocardial calcification can gradually subside and the cardiac function can gradually recover. For FM patients, timely and comprehensive intensive treatment, including heart, lung, and kidney replacement therapy and early administration of hormone preparations, may be beneficial to the early recovery of patients. Oxford University Press 2023-07-13 /pmc/articles/PMC10405352/ /pubmed/37554960 http://dx.doi.org/10.1093/ehjcr/ytad302 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Case Report
You, Binquan
Zeng, Congjun
Wang, Bingyin
Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title_full Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title_fullStr Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title_full_unstemmed Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title_short Ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
title_sort ultra-early myocardial calcification secondary to fulminant myocarditis with 4 years of follow-up: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405352/
https://www.ncbi.nlm.nih.gov/pubmed/37554960
http://dx.doi.org/10.1093/ehjcr/ytad302
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