Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts

BACKGROUND: Genetic and metabolic heterogeneity are well-known features of cancer and tumors can be viewed as an evolving mix of subclonal populations, subjected to selection driven by microenvironmental pressures or drug treatment. In previous studies, anti-VEGF therapy was found to elicit rewiring...

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Detalles Bibliográficos
Autores principales: Boso, Daniele, Tognon, Martina, Curtarello, Matteo, Minuzzo, Sonia, Piga, Ilaria, Brillo, Valentina, Lazzarini, Elisabetta, Carlet, Jessica, Marra, Ludovica, Trento, Chiara, Rasola, Andrea, Masgras, Ionica, Caporali, Leonardo, Del Ben, Fabio, Brisotto, Giulia, Turetta, Matteo, Pastorelli, Roberta, Brunelli, Laura, Navaglia, Filippo, Esposito, Giovanni, Grassi, Angela, Indraccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405561/
https://www.ncbi.nlm.nih.gov/pubmed/37550722
http://dx.doi.org/10.1186/s13046-023-02779-x

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