Identification of the γ-glutamyl cycle as a novel therapeutic target and 5-oxoproline as a new biomarker for diagnosing pancreatic cancer

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignant solid tumours, and abnormal metabolic reprogramming in the tumour microenvironment is regarded as an important contributor to its pathogenesis. OBJECTIVES: As there is an urgency to identify new targets based on...

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Detalles Bibliográficos
Autores principales: Wang, Weijia, Tian, Xiuyun, Yan, Liang, Guan, Xiaoya, Dong, Bin, Zhao, Min, Liu, Daoning, Wu, Jianhui, Hao, Chunyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405758/
https://www.ncbi.nlm.nih.gov/pubmed/37544888
http://dx.doi.org/10.1080/07853890.2023.2242247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405758/
https://www.ncbi.nlm.nih.gov/pubmed/37544888
http://dx.doi.org/10.1080/07853890.2023.2242247

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