OX40L-Armed Oncolytic Virus Boosts T-cell Response and Remodels Tumor Microenvironment for Pancreatic Cancer Treatment

Rationale: The resistance of pancreatic ductal adenocarcinoma (PDAC) to immunotherapies is caused by the immunosuppressive tumor microenvironment (TME) and dense extracellular matrix. Currently, the efficacy of an isolated strategy targeting stromal desmoplasia or immune cells has been met with limi...

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Detalles Bibliográficos
Autores principales: Liu, Shiyu, Li, Fan, Ma, Qiongqiong, Du, Mingjuan, Wang, Haoran, Zhu, Yiping, Deng, Li, Gao, Wenrui, Wang, Chunlei, Liu, Yanqin, Zhao, Zhuoqian, Liu, Huanzhen, Wang, Ruikun, Tian, Yujie, Hu, Manli, Wan, Yajuan, Lu, Wenyi, Zhang, Meng, Zhao, Mingfeng, Cao, Youjia, Zhang, Hongkai, Wang, Wei, Wang, Hui, Wang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405835/
https://www.ncbi.nlm.nih.gov/pubmed/37554264
http://dx.doi.org/10.7150/thno.83495

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