Caveolin-mediated cytosolic delivery of spike nanoparticle enhances antitumor immunity of neoantigen vaccine for hepatocellular carcinoma

Rationale: Although neoantigen-based cancer vaccines have shown promise in various solid tumors, limited immune responses and clinical outcomes have been reported in patients with advanced disease. Cytosolic transport of neoantigen and adjuvant is required for the activation of intracellular Toll-li...

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Detalles Bibliográficos
Autores principales: Lin, Zhiwen, Jiang, Chenwei, Wang, Peiyuan, Chen, Qingjing, Wang, Bing, Fu, Xinyue, Liang, Yuzhi, Zhang, Da, Zeng, Yongyi, Liu, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405843/
https://www.ncbi.nlm.nih.gov/pubmed/37554274
http://dx.doi.org/10.7150/thno.85843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405843/
https://www.ncbi.nlm.nih.gov/pubmed/37554274
http://dx.doi.org/10.7150/thno.85843

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