Cargando…

Thymosin β4 Alleviates Autoimmune Dacryoadenitis via Suppressing Th17 Cell Response

PURPOSE: We investigated the therapeutic effect of recombinant thymosin β4 (rTβ4) on rabbit autoimmune dacryoadenitis, an animal model of SS dry eye, and explore its mechanisms. METHODS: Rabbits were treated topically with rTβ4 or PBS solution after disease onset for 28 days, and clinical scores wer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Xiaoyu, Li, Na, Yang, Ning, Mi, Baoyue, Dang, Weiyu, Sun, Deming, Ma, Shanshan, Nian, Hong, Wei, Ruihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Immunology and Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405860/ https://www.ncbi.nlm.nih.gov/pubmed/37531112 http://dx.doi.org/10.1167/iovs.64.11.3

Ejemplares similares

PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice
por: Guo, Xingyi, et al.
Publicado: (2022)

Mesenchymal stem cells for treating autoimmune dacryoadenitis
por: Lu, Xiaoxiao, et al.
Publicado: (2017)

Adipose-Derived Mesenchymal Stem Cells Reduce Lymphocytic Infiltration in a Rabbit Model of Induced Autoimmune Dacryoadenitis
por: Li, Xue, et al.
Publicado: (2018)

MicroRNA expression profile of Lacrimal Glands in rabbit autoimmune dacryoadenitis model
por: Liu, Bo, et al.
Publicado: (2020)

MSC-Derived Small Extracellular Vesicles Attenuate Autoimmune Dacryoadenitis by Promoting M2 Macrophage Polarization and Inducing Tregs via miR-100-5p
por: Li, Na, et al.
Publicado: (2022)

Bilateral dacryoadenitis
por: Derr, Charlotte, et al.
Publicado: (2012)

Idiopathic sclerosing dacryoadenitis
por: Butterfield, Samantha D., et al.
Publicado: (2023)

Parthenolide Suppresses T Helper 17 and Alleviates Experimental Autoimmune Encephalomyelitis
por: Zhang, Zhihui, et al.
Publicado: (2022)

The miRNA Landscape of Lacrimal Glands in a Murine Model of Autoimmune Dacryoadenitis
por: Singh Kakan, Shruti, et al.
Publicado: (2023)

Silybin Alleviates Experimental Autoimmune Encephalomyelitis by Suppressing Dendritic Cell Activation and Th17 Cell Differentiation
por: Yang, Huan-Li, et al.
Publicado: (2021)

Effect of thymosin alpha-1 on subpopulations of Th1, Th2, Th17, and regulatory T cells (Tregs) in vitro
por: Yang, Xia, et al.
Publicado: (2011)

Na(+)/K(+)-ATPase in the lacrimal glands of rabbits and its changes during induced autoimmune dacryoadenitis
por: Ding, Chuanqing, et al.
Publicado: (2011)

First case report of isolated aspergillus dacryoadenitis
por: Acharya, Ishan, et al.
Publicado: (2016)

Epidemic Keratoconjunctivitis-Associated Acute Dacryoadenitis in an Adult
por: Takahashi, Yasuhiro, et al.
Publicado: (2022)

Dacryoadenitis post COVID-19 infection and immunization
por: Singh, Saumika, et al.
Publicado: (2023)

Bidirectional Effect of IFN-γ on Th17 Responses in Experimental Autoimmune Uveitis
por: Shao, Hui, et al.
Publicado: (2022)

The Role of Adenosine in γδ T-Cell Regulation of Th17 Responses in Experimental Autoimmune Uveitis
por: Shao, Hui, et al.
Publicado: (2023)

The pathological features of ectopic lymphoid neogenesis in idiopathic dacryoadenitis
por: Guo, Jie, et al.
Publicado: (2016)

Dacryoadenitis with Ptosis and Diplopia as the Initial Presentation of Granulomatosis with Polyangiitis
por: Hibino, Makoto, et al.
Publicado: (2017)

Epstein-Barr Virus Dacryoadenitis in a Young Woman
por: Watanabe, Tamami, et al.
Publicado: (2022)

Orbital Inflammation and Dacryoadenitis after COVID-19 Vaccination
por: Jalink, Maarten B., et al.
Publicado: (2022)

Heterochronic Parabiosis Causes Dacryoadenitis in Young Lacrimal Glands
por: Scholand, Kaitlin K., et al.
Publicado: (2023)

Bilateral Dacryoadenitis As the First Presentation in an Undiagnosed Sarcoidosis Patient
por: Saifi, Motaz, et al.
Publicado: (2023)

Fenofibrate treatment of rats with experimental autoimmune myocarditis by alleviating Treg/Th17 disorder
por: Cheng, Huilei, et al.
Publicado: (2016)

Systemic gene therapy with thymosin β4 alleviates glomerular injury in mice
por: Mason, William J., et al.
Publicado: (2022)

Acute Painful Ptosis Secondary to IgG4 Dacryoadenitis
por: Hussain, Rumana, et al.
Publicado: (2016)

Tozinameran: Acute dacryoadenitis and orbital inflammatory syndrome: case report
Publicado: (2022)

Acute Dacryoadenitis due to Primary Epstein-Barr Virus Infection
por: Hayano, Satoshi, et al.
Publicado: (2022)

Clinical Images: Dacryoadenitis as the herald symptom for systemic lupus erythematosus
por: Sullivan, Megan M., et al.
Publicado: (2023)

Adenosine receptor ligation tips the uveitogenic Th1 and Th17 balance towards the latter in experimental autoimmune uveitis-induced mouse
por: Sun, Deming, et al.
Publicado: (2021)

Thymosin Beta 4 and Thymosin Beta 10 Expression in Hepatocellular Carcinoma
por: Theunissen, W., et al.
Publicado: (2014)

LncRNA Neat1 targets NonO and miR-128-3p to promote antigen-specific Th17 cell responses and autoimmune inflammation
por: Chen, Sisi, et al.
Publicado: (2023)

CD73(+) Dendritic Cells in Cascading Th17 Responses of Experimental Autoimmune Uveitis-Induced Mice
por: Ko, MinHee K., et al.
Publicado: (2020)

Severe anterior uveitis associated with idiopathic dacryoadenitis in diabetes mellitus patient
por: Takahashi, Yasuhiro, et al.
Publicado: (2011)

Bilateral dacryoadenitis in adult-onset Still’s disease: A case report
por: Huang, Qing, et al.
Publicado: (2022)

Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo
por: Guendisch, Ulf, et al.
Publicado: (2017)

Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation
por: Tan, Jun, et al.
Publicado: (2020)

Th17 Cells in Immunity and Autoimmunity
por: Bedoya, Simone Kennedy, et al.
Publicado: (2013)

Pien Tze Huang Alleviates Relapsing-Remitting Experimental Autoimmune Encephalomyelitis Mice by Regulating Th1 and Th17 Cells
por: Qiu, Xuemei, et al.
Publicado: (2018)

Suppression of thymosin β10 increases cell migration and metastasis of cholangiocarcinoma
por: Sribenja, Sirinapa, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3bg98atl571uhv0vr3kfh7q1gs