Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case

Primary central nervous system lymphoma (PCNSL) is an uncommon malignancy of B-cell origin that typically involves the brain, eyes, and spinal cord without systemic spread. PCNSL typically involves the cerebral hemispheres, basal ganglia, or periventricular region. Isolated leptomeningeal PCNSL with...

Descripción completa

Detalles Bibliográficos
Autores principales: Lobban, Geoffrey B, Luke, Alex J, Basta, Peter, Laziuk, Katsiaryna, Kalra, Amandeep, Kulhari, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405868/
https://www.ncbi.nlm.nih.gov/pubmed/37554597
http://dx.doi.org/10.7759/cureus.41561
_version_ 1785085628633841664
author Lobban, Geoffrey B
Luke, Alex J
Basta, Peter
Laziuk, Katsiaryna
Kalra, Amandeep
Kulhari, Ashish
author_facet Lobban, Geoffrey B
Luke, Alex J
Basta, Peter
Laziuk, Katsiaryna
Kalra, Amandeep
Kulhari, Ashish
author_sort Lobban, Geoffrey B
collection PubMed
description Primary central nervous system lymphoma (PCNSL) is an uncommon malignancy of B-cell origin that typically involves the brain, eyes, and spinal cord without systemic spread. PCNSL typically involves the cerebral hemispheres, basal ganglia, or periventricular region. Isolated leptomeningeal PCNSL without any evidence of parenchymal involvement is very rare. We present a very unusual case of PCNSL presenting as persistent bilateral Bell's palsy and trigeminal neuralgia with magnetic resonance imaging (MRI) brain showing significantly hypertrophied enhancing bilateral facial and trigeminal nerves. 
format Online
Article
Text
id pubmed-10405868
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-104058682023-08-08 Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case Lobban, Geoffrey B Luke, Alex J Basta, Peter Laziuk, Katsiaryna Kalra, Amandeep Kulhari, Ashish Cureus Neurology Primary central nervous system lymphoma (PCNSL) is an uncommon malignancy of B-cell origin that typically involves the brain, eyes, and spinal cord without systemic spread. PCNSL typically involves the cerebral hemispheres, basal ganglia, or periventricular region. Isolated leptomeningeal PCNSL without any evidence of parenchymal involvement is very rare. We present a very unusual case of PCNSL presenting as persistent bilateral Bell's palsy and trigeminal neuralgia with magnetic resonance imaging (MRI) brain showing significantly hypertrophied enhancing bilateral facial and trigeminal nerves.  Cureus 2023-07-08 /pmc/articles/PMC10405868/ /pubmed/37554597 http://dx.doi.org/10.7759/cureus.41561 Text en Copyright © 2023, Lobban et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurology
Lobban, Geoffrey B
Luke, Alex J
Basta, Peter
Laziuk, Katsiaryna
Kalra, Amandeep
Kulhari, Ashish
Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title_full Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title_fullStr Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title_full_unstemmed Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title_short Primary Central Nervous System Lymphoma Presenting as Isolated Multiple Cranial Neuropathies: An Extremely Rare Case
title_sort primary central nervous system lymphoma presenting as isolated multiple cranial neuropathies: an extremely rare case
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405868/
https://www.ncbi.nlm.nih.gov/pubmed/37554597
http://dx.doi.org/10.7759/cureus.41561
work_keys_str_mv AT lobbangeoffreyb primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase
AT lukealexj primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase
AT bastapeter primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase
AT laziukkatsiaryna primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase
AT kalraamandeep primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase
AT kulhariashish primarycentralnervoussystemlymphomapresentingasisolatedmultiplecranialneuropathiesanextremelyrarecase

Ejemplares similares