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In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129

Abnormal aggregation of the α-synuclein protein is a key molecular feature of Parkinson’s disease and other neurodegenerative diseases. The precise mechanisms that trigger α-synuclein aggregation are unclear, and it is not known what role aggregation plays in disease pathogenesis. Here we use an in...

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Detalles Bibliográficos
Autores principales:	Weston, Leah J., Cook, Zoe T., Stackhouse, Teresa L., Sal, Mehtab K., Schultz, Baergen I., Tobias, Zachary J.C., Osterberg, Valerie R., Brockway, Nicole L., Pizano, Saheli, Glover, Greta, Weissman, Tamily A., Unni, Vivek K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10405908/ https://www.ncbi.nlm.nih.gov/pubmed/33556542 http://dx.doi.org/10.1016/j.nbd.2021.105291

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