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Mismatch repair protein mutations in isocitrate dehydrogenase (IDH)-mutant astrocytoma and IDH-wild-type glioblastoma

BACKGROUND: Mutations in mismatch repair (MMR) genes (MSH2, MSH6, MLH1, and PMS2) are associated with microsatellite instability and a hypermutator phenotype in numerous systemic cancers, and germline MMR mutations have been implicated in multi-organ tumor syndromes. In gliomas, MMR mutations can fu...

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Detalles Bibliográficos
Autores principales:	Richardson, Timothy E, Yokoda, Raquel T, Rashidipour, Omid, Vij, Meenakshi, Snuderl, Matija, Brem, Steven, Hatanpaa, Kimmo J, McBrayer, Samuel K, Abdullah, Kalil G, Umphlett, Melissa, Walker, Jamie M, Tsankova, Nadejda M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Clinical Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406418/ https://www.ncbi.nlm.nih.gov/pubmed/37554222 http://dx.doi.org/10.1093/noajnl/vdad085

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