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Regulation of store-operated Ca(2+) entry by IP(3) receptors independent of their ability to release Ca(2+)
Loss of endoplasmic reticular (ER) Ca(2+) activates store-operated Ca(2+) entry (SOCE) by causing the ER localized Ca(2+) sensor STIM to unfurl domains that activate Orai channels in the plasma membrane at membrane contact sites (MCS). Here, we demonstrate a novel mechanism by which the inositol 1,4...
Autores principales: | Chakraborty, Pragnya, Deb, Bipan Kumar, Arige, Vikas, Musthafa, Thasneem, Malik, Sundeep, Yule, David I, Taylor, Colin W, Hasan, Gaiti |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406432/ https://www.ncbi.nlm.nih.gov/pubmed/37466241 http://dx.doi.org/10.7554/eLife.80447 |
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