Functional Epicardial Conduction Disturbances Due to a SCN5A Variant Associated With Brugada Syndrome

BACKGROUND: Brugada syndrome is a significant cause of sudden cardiac death (SCD), but the underlying mechanisms remain hypothetical. OBJECTIVES: This study aimed to elucidate this knowledge gap through detailed ex vivo human heart studies. METHODS: A heart was obtained from a 15-year-old adolescent...

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Detalles Bibliográficos
Autores principales: Renard, Estelle, Walton, Richard D., Benoist, David, Brette, Fabien, Bru-Mercier, Gilles, Chaigne, Sébastien, Charron, Sabine, Constantin, Marion, Douard, Matthieu, Dubes, Virginie, Guillot, Bastien, Hof, Thomas, Magat, Julie, Martinez, Marine E., Michel, Cindy, Pallares-Lupon, Néstor, Pasdois, Philippe, Récalde, Alice, Vaillant, Fanny, Sacher, Frédéric, Labrousse, Louis, Rogier, Julien, Kyndt, Florence, Baudic, Manon, Schott, Jean-Jacques, Barc, Julien, Probst, Vincent, Sarlandie, Marine, Marionneau, Céline, Ashton, Jesse L., Hocini, Mélèze, Haïssaguerre, Michel, Bernus, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406612/
https://www.ncbi.nlm.nih.gov/pubmed/37227351
http://dx.doi.org/10.1016/j.jacep.2023.03.009

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