Plasma Heparin Cofactor II Activity Is Inversely Associated with Hepatic Fibrosis of Non-Alcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus

Aims: Thrombin exerts various pathophysiological functions by activating protease-activated receptors (PARs), and thrombin-induced activation of PARs promotes the development of non-alcoholic fatty liver disease (NAFLD). Since heparin cofactor II (HCII) specifically inactivates thrombin action, we h...

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Detalles Bibliográficos
Autores principales: Hara, Tomoyo, Uemoto, Ryoko, Sekine, Akiko, Mitsui, Yukari, Masuda, Shiho, Yamagami, Hiroki, Kurahashi, Kiyoe, Yoshida, Sumiko, Otoda, Toshiki, Yuasa, Tomoyuki, Kuroda, Akio, Ikeda, Yasumasa, Endo, Itsuro, Honda, Soichi, Yoshimoto, Katsuhiko, Kondo, Akira, Tamaki, Toshiaki, Matsumoto, Toshio, Matsuhisa, Munehide, Abe, Masahiro, Aihara, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406648/
https://www.ncbi.nlm.nih.gov/pubmed/36244745
http://dx.doi.org/10.5551/jat.63752

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