Desmin mutations impact the autophagy flux in C2C12 cell in mutation-specific manner

Desmin is the main intermediate filament of striated and smooth muscle cells and plays a crucial role in maintaining the stability of muscle fiber during contraction and relaxation cycles. Being a component of Z-disk area, desmin integrates autophagic pathways, and the disturbance of Z-disk proteins...

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Detalles Bibliográficos
Autores principales: Sukhareva, K. S., Smolina, N. A., Churkina, A. I., Kalugina, K. K., Zhuk, S. V., Khudiakov, A. A., Khodot, A. A., Faggian, G., Luciani, G. B., Sejersen, T., Kostareva, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406715/
https://www.ncbi.nlm.nih.gov/pubmed/37277577
http://dx.doi.org/10.1007/s00441-023-03790-6

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