Experimental and spontaneous metastasis assays can result in divergence in clonal architecture

Intratumoural heterogeneity is associated with poor outcomes in breast cancer. To understand how malignant clones survive and grow in metastatic niches, in vivo models using cell lines and patient-derived xenografts (PDX) have become the gold standard. Injections of cancer cells in orthotopic sites...

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Detalles Bibliográficos
Autores principales: Serrano, Antonin, Weber, Tom, Berthelet, Jean, El-Saafin, Farrah, Gadipally, Sreeja, Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Mariadason, John M., Oakes, Samantha R., Britt, Kara, Naik, Shalin H., Merino, Delphine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406815/
https://www.ncbi.nlm.nih.gov/pubmed/37550477
http://dx.doi.org/10.1038/s42003-023-05167-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406815/
https://www.ncbi.nlm.nih.gov/pubmed/37550477
http://dx.doi.org/10.1038/s42003-023-05167-5

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