CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma

MAD2 is a spindle assembly checkpoint protein that participates in the formation of mitotic checkpoint complex, which blocks mitotic progression. RNF8, an established DNA damage response protein, has been implicated in mitotic checkpoint regulation but its exact role remains poorly understood. Here,...

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Detalles Bibliográficos
Autores principales: Chuah, You Heng, Tay, Emmy Xue Yun, Grinchuk, Oleg V., Yoon, Jeehyun, Feng, Jia, Kannan, Srinivasaraghavan, Robert, Matius, Jakhar, Rekha, Liang, Yajing, Lee, Bernice Woon Li, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Lu, Guang, Low, Boon Chuan, Crasta, Karen Carmelina, Verma, Chandra Shekhar, Lin, Zhewang, Ong, Derrick Sek Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406836/
https://www.ncbi.nlm.nih.gov/pubmed/37468549
http://dx.doi.org/10.1038/s41418-023-01192-3

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