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SONAR enables cell type deconvolution with spatially weighted Poisson-Gamma model for spatial transcriptomics

Recent advancements in spatial transcriptomic technologies have enabled the measurement of whole transcriptome profiles with preserved spatial context. However, limited by spatial resolution, the measured expressions at each spot are often from a mixture of multiple cells. Computational deconvolutio...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyuan, Wu, Dafei, Zhai, Weiwei, Ma, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10406862/
https://www.ncbi.nlm.nih.gov/pubmed/37550279
http://dx.doi.org/10.1038/s41467-023-40458-9