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Androgen receptor transcriptional activity is required for heregulin-1β–mediated nuclear localization of the HER3/ErbB3 receptor tyrosine kinase

Prostate cancer is initially regulated by the androgen receptor (AR), a ligand-activated, transcription factor, and is in a hormone-dependent state (hormone-sensitive prostate cancer (HSPC)), but eventually becomes androgen-refractory (castration-resistant prostate cancer (CRPC)) because of mechanis...

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Detalles Bibliográficos
Autores principales: Jathal, Maitreyee K., Siddiqui, Salma, Vasilatis, Demitria M., Durbin Johnson, Blythe P., Drake, Christiana, Mooso, Benjamin A., D’Abronzo, Leandro S., Batra, Neelu, Mudryj, Maria, Ghosh, Paramita M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407237/
https://www.ncbi.nlm.nih.gov/pubmed/37380074
http://dx.doi.org/10.1016/j.jbc.2023.104973

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