Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection

Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman wi...

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Autores principales: Hamada, Toru, Katsuta, Tomoya, Aibara, Kento, Nozu, Shohei, Nakamura, Junya, Kondo, Haruka, Tachibana, Sayaka, Inoue, Koji, Nakanishi, Norihiko, Moritaka, Tomonori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407267/
https://www.ncbi.nlm.nih.gov/pubmed/37560613
http://dx.doi.org/10.1016/j.rmcr.2023.101890
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author Hamada, Toru
Katsuta, Tomoya
Aibara, Kento
Nozu, Shohei
Nakamura, Junya
Kondo, Haruka
Tachibana, Sayaka
Inoue, Koji
Nakanishi, Norihiko
Moritaka, Tomonori
author_facet Hamada, Toru
Katsuta, Tomoya
Aibara, Kento
Nozu, Shohei
Nakamura, Junya
Kondo, Haruka
Tachibana, Sayaka
Inoue, Koji
Nakanishi, Norihiko
Moritaka, Tomonori
author_sort Hamada, Toru
collection PubMed
description Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman with ABPA who was diagnosed with hepatitis B and active hepatitis C, and sputum analysis revealed the presence of bacteria. Oral steroids were initially administered, but the patient was switched to mepolizumab because of numerous infectious complications. The early introduction of mepolizumab is effective in patients with ABPA complicated by infectious diseases.
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spelling pubmed-104072672023-08-09 Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection Hamada, Toru Katsuta, Tomoya Aibara, Kento Nozu, Shohei Nakamura, Junya Kondo, Haruka Tachibana, Sayaka Inoue, Koji Nakanishi, Norihiko Moritaka, Tomonori Respir Med Case Rep Case Report Allergic bronchopulmonary aspergillosis (ABPA) is an allergic reaction caused by the fungus Aspergillus, and it is often treated with steroids or antifungal agents. However, long-term use of these medications can lead to infections and drug interactions. We present the case of a 71-year-old woman with ABPA who was diagnosed with hepatitis B and active hepatitis C, and sputum analysis revealed the presence of bacteria. Oral steroids were initially administered, but the patient was switched to mepolizumab because of numerous infectious complications. The early introduction of mepolizumab is effective in patients with ABPA complicated by infectious diseases. Elsevier 2023-07-16 /pmc/articles/PMC10407267/ /pubmed/37560613 http://dx.doi.org/10.1016/j.rmcr.2023.101890 Text en © 2023 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Hamada, Toru
Katsuta, Tomoya
Aibara, Kento
Nozu, Shohei
Nakamura, Junya
Kondo, Haruka
Tachibana, Sayaka
Inoue, Koji
Nakanishi, Norihiko
Moritaka, Tomonori
Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title_full Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title_fullStr Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title_full_unstemmed Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title_short Mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
title_sort mepolizumab in allergic bronchopulmonary aspergillosis complicated by infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407267/
https://www.ncbi.nlm.nih.gov/pubmed/37560613
http://dx.doi.org/10.1016/j.rmcr.2023.101890
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