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Oncolytic viruses and antibodies: are they more successful when delivered separately or when engineered as a single agent?
Oncolytic viruses (OVs) provide the promise of tumor-selective cytotoxicity coupled with amplification of the therapeutic agent (the virus) in situ within the tumor improving its therapeutic index. Despite this promise, however, single agent-treatments have not been as successful as combination ther...
Autores principales: | Wan, Peter Kok-Ting, Fernandes, Ricardo A, Seymour, Leonard W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407364/ https://www.ncbi.nlm.nih.gov/pubmed/37541690 http://dx.doi.org/10.1136/jitc-2022-006518 |
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