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The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation inju...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407490/ https://www.ncbi.nlm.nih.gov/pubmed/37559626 http://dx.doi.org/10.21037/jtd-22-1734 |
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author | Ravikumar, Nakul Ho, Elliot Wagh, Ajay Murgu, Septimiu |
author_facet | Ravikumar, Nakul Ho, Elliot Wagh, Ajay Murgu, Septimiu |
author_sort | Ravikumar, Nakul |
collection | PubMed |
description | Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation injury and iatrogenic factors such as post-intubation and post-tracheostomy. Once suspected, tracheal strictures are diagnosed by performing a thorough evaluation involving clinical exam, laboratory workup, pulmonary function test, chest imaging and bronchoscopy. Bronchoscopy plays a pivotal role in the diagnosis of stenosis and along with the imaging and physiologic assessments leads to a proper description of the stenosis based on all parameters that matters for management. Surgical resection provides a definitive management in most patients with idiopathic or post intubation/tracheostomy stenosis, however, factors such as severe co-morbidities, length and location of the stricture can preclude patients from undergoing curative surgery. Several bronchoscopic interventions including mechanical or laser assisted dilation, electrosurgery (ES), airway stenting and pharmacological treatment with mitomycin C (MMC) and intralesional steroid have been reported in the literature for management of patients who are not surgical candidates. Herein, we review the role of bronchoscopy and illustrate the importance of a multi-disciplinary team (MDT) approach comprising of interventional pulmonologists, thoracic surgeons and otorhinolaryngologists in the diagnosis and management of patients with benign tracheal stenosis. |
format | Online Article Text |
id | pubmed-10407490 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AME Publishing Company |
record_format | MEDLINE/PubMed |
spelling | pubmed-104074902023-08-09 The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis Ravikumar, Nakul Ho, Elliot Wagh, Ajay Murgu, Septimiu J Thorac Dis Review Article Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation injury and iatrogenic factors such as post-intubation and post-tracheostomy. Once suspected, tracheal strictures are diagnosed by performing a thorough evaluation involving clinical exam, laboratory workup, pulmonary function test, chest imaging and bronchoscopy. Bronchoscopy plays a pivotal role in the diagnosis of stenosis and along with the imaging and physiologic assessments leads to a proper description of the stenosis based on all parameters that matters for management. Surgical resection provides a definitive management in most patients with idiopathic or post intubation/tracheostomy stenosis, however, factors such as severe co-morbidities, length and location of the stricture can preclude patients from undergoing curative surgery. Several bronchoscopic interventions including mechanical or laser assisted dilation, electrosurgery (ES), airway stenting and pharmacological treatment with mitomycin C (MMC) and intralesional steroid have been reported in the literature for management of patients who are not surgical candidates. Herein, we review the role of bronchoscopy and illustrate the importance of a multi-disciplinary team (MDT) approach comprising of interventional pulmonologists, thoracic surgeons and otorhinolaryngologists in the diagnosis and management of patients with benign tracheal stenosis. AME Publishing Company 2023-06-28 2023-07-31 /pmc/articles/PMC10407490/ /pubmed/37559626 http://dx.doi.org/10.21037/jtd-22-1734 Text en 2023 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) . |
spellingShingle | Review Article Ravikumar, Nakul Ho, Elliot Wagh, Ajay Murgu, Septimiu The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title | The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title_full | The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title_fullStr | The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title_full_unstemmed | The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title_short | The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
title_sort | role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407490/ https://www.ncbi.nlm.nih.gov/pubmed/37559626 http://dx.doi.org/10.21037/jtd-22-1734 |
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