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The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis

Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation inju...

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Autores principales: Ravikumar, Nakul, Ho, Elliot, Wagh, Ajay, Murgu, Septimiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407490/
https://www.ncbi.nlm.nih.gov/pubmed/37559626
http://dx.doi.org/10.21037/jtd-22-1734
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author Ravikumar, Nakul
Ho, Elliot
Wagh, Ajay
Murgu, Septimiu
author_facet Ravikumar, Nakul
Ho, Elliot
Wagh, Ajay
Murgu, Septimiu
author_sort Ravikumar, Nakul
collection PubMed
description Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation injury and iatrogenic factors such as post-intubation and post-tracheostomy. Once suspected, tracheal strictures are diagnosed by performing a thorough evaluation involving clinical exam, laboratory workup, pulmonary function test, chest imaging and bronchoscopy. Bronchoscopy plays a pivotal role in the diagnosis of stenosis and along with the imaging and physiologic assessments leads to a proper description of the stenosis based on all parameters that matters for management. Surgical resection provides a definitive management in most patients with idiopathic or post intubation/tracheostomy stenosis, however, factors such as severe co-morbidities, length and location of the stricture can preclude patients from undergoing curative surgery. Several bronchoscopic interventions including mechanical or laser assisted dilation, electrosurgery (ES), airway stenting and pharmacological treatment with mitomycin C (MMC) and intralesional steroid have been reported in the literature for management of patients who are not surgical candidates. Herein, we review the role of bronchoscopy and illustrate the importance of a multi-disciplinary team (MDT) approach comprising of interventional pulmonologists, thoracic surgeons and otorhinolaryngologists in the diagnosis and management of patients with benign tracheal stenosis.
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spelling pubmed-104074902023-08-09 The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis Ravikumar, Nakul Ho, Elliot Wagh, Ajay Murgu, Septimiu J Thorac Dis Review Article Benign tracheal stenosis can cause dyspnea, wheezing, and cough mimicking other obstructive lung diseases which often leads to a delay in the diagnosis. Risk factors and etiologies for tracheal strictures include autoimmune diseases, infection, gastro-esophageal reflux disease (GERD), radiation injury and iatrogenic factors such as post-intubation and post-tracheostomy. Once suspected, tracheal strictures are diagnosed by performing a thorough evaluation involving clinical exam, laboratory workup, pulmonary function test, chest imaging and bronchoscopy. Bronchoscopy plays a pivotal role in the diagnosis of stenosis and along with the imaging and physiologic assessments leads to a proper description of the stenosis based on all parameters that matters for management. Surgical resection provides a definitive management in most patients with idiopathic or post intubation/tracheostomy stenosis, however, factors such as severe co-morbidities, length and location of the stricture can preclude patients from undergoing curative surgery. Several bronchoscopic interventions including mechanical or laser assisted dilation, electrosurgery (ES), airway stenting and pharmacological treatment with mitomycin C (MMC) and intralesional steroid have been reported in the literature for management of patients who are not surgical candidates. Herein, we review the role of bronchoscopy and illustrate the importance of a multi-disciplinary team (MDT) approach comprising of interventional pulmonologists, thoracic surgeons and otorhinolaryngologists in the diagnosis and management of patients with benign tracheal stenosis. AME Publishing Company 2023-06-28 2023-07-31 /pmc/articles/PMC10407490/ /pubmed/37559626 http://dx.doi.org/10.21037/jtd-22-1734 Text en 2023 Journal of Thoracic Disease. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Article
Ravikumar, Nakul
Ho, Elliot
Wagh, Ajay
Murgu, Septimiu
The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title_full The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title_fullStr The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title_full_unstemmed The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title_short The role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
title_sort role of bronchoscopy in the multidisciplinary approach to benign tracheal stenosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407490/
https://www.ncbi.nlm.nih.gov/pubmed/37559626
http://dx.doi.org/10.21037/jtd-22-1734
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