Thymic epithelial cell fate and potency in early organogenesis assessed by single cell transcriptional and functional analysis

During development, cortical (c) and medullary (m) thymic epithelial cells (TEC) arise from the third pharyngeal pouch endoderm. Current models suggest that within the thymic primordium most TEC exist in a bipotent/common thymic epithelial progenitor cell (TEPC) state able to generate both cTEC and...

Descripción completa

Detalles Bibliográficos
Autores principales: Farley, Alison Mary, Chengrui, An, Palmer, Sam, Liu, Dong, Kousa, Anastasia I., Rouse, Paul, Major, Viktoria, Sweetman, Joanna, Morys, Jan, Corsinotti, Andrea, Nichols, Jennifer, Ure, Janice, McLay, Renee, Boulter, Luke, Chapman, S. Jon, Tomlinson, Simon R., Blackburn, C. Clare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407560/
https://www.ncbi.nlm.nih.gov/pubmed/37559721
http://dx.doi.org/10.3389/fimmu.2023.1202163

Ejemplares similares

Ejemplares similares