The NLRP3 inflammasome in viral infection (Review)

The interplay between pathogen and host determines the immune response during viral infection. The Nod-like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL-1β, which play an important role in the innate immune...

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Detalles Bibliográficos
Autores principales: Zheng, Qiaoli, Hua, Chunting, Liang, Qichang, Cheng, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407610/
https://www.ncbi.nlm.nih.gov/pubmed/37417336
http://dx.doi.org/10.3892/mmr.2023.13047
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author Zheng, Qiaoli
Hua, Chunting
Liang, Qichang
Cheng, Hao
author_facet Zheng, Qiaoli
Hua, Chunting
Liang, Qichang
Cheng, Hao
author_sort Zheng, Qiaoli
collection PubMed
description The interplay between pathogen and host determines the immune response during viral infection. The Nod-like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL-1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed.
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spelling pubmed-104076102023-08-09 The NLRP3 inflammasome in viral infection (Review) Zheng, Qiaoli Hua, Chunting Liang, Qichang Cheng, Hao Mol Med Rep Review The interplay between pathogen and host determines the immune response during viral infection. The Nod-like receptor (NLR) protein 3 inflammasome is a multiprotein complex that induces the activation of inflammatory caspases and the release of IL-1β, which play an important role in the innate immune responses. In the present review, the mechanisms of the NLR family pyrin domain containing 3 inflammasome activation and its dysregulation in viral infection were addressed. D.A. Spandidos 2023-07-06 /pmc/articles/PMC10407610/ /pubmed/37417336 http://dx.doi.org/10.3892/mmr.2023.13047 Text en Copyright: © Zheng et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Review
Zheng, Qiaoli
Hua, Chunting
Liang, Qichang
Cheng, Hao
The NLRP3 inflammasome in viral infection (Review)
title The NLRP3 inflammasome in viral infection (Review)
title_full The NLRP3 inflammasome in viral infection (Review)
title_fullStr The NLRP3 inflammasome in viral infection (Review)
title_full_unstemmed The NLRP3 inflammasome in viral infection (Review)
title_short The NLRP3 inflammasome in viral infection (Review)
title_sort nlrp3 inflammasome in viral infection (review)
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407610/
https://www.ncbi.nlm.nih.gov/pubmed/37417336
http://dx.doi.org/10.3892/mmr.2023.13047
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