Kartogenin-enhanced dynamic hydrogel ameliorates intervertebral disc degeneration via restoration of local redox homeostasis

INTRODUCTION: Over-activation of oxidative stress due to impaired antioxidant functions in nucleus pulpous (NP) has been identified as a key factor contributing to intervertebral disc degeneration (IVDD). While Kartogenin (KGN) has previously demonstrated antioxidant properties on articular cartilag...

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Detalles Bibliográficos
Autores principales: Tian, Xin, Zhang, Yijian, Shen, Lei, Pan, Guoqing, Yang, Huilin, Jiang, Zhenhuan, Zhu, Xuesong, He, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407629/
https://www.ncbi.nlm.nih.gov/pubmed/37560412
http://dx.doi.org/10.1016/j.jot.2023.07.002

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