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Melatonin acts synergistically with pazopanib against renal cell carcinoma cells through p38 mitogen-activated protein kinase-mediated mitochondrial and autophagic apoptosis
BACKGROUND: Mounting evidence indicates that melatonin has possible activity against different tumors. Pazopanib is an anticancer drug used to treat renal cell carcinoma (RCC). This study tested the anticancer activity of melatonin combined with pazopanib on RCC cells and explored the underlying mec...
Autores principales: | Lai, Chien-Pin, Chen, Yong-Syuan, Ying, Tsung-Ho, Kao, Cheng-Yen, Chiou, Hui-Ling, Kao, Shao-Hsuan, Hsieh, Yi-Hsien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Nephrology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407642/ https://www.ncbi.nlm.nih.gov/pubmed/37165617 http://dx.doi.org/10.23876/j.krcp.22.114 |
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