Continuous, but not intermittent, regimens of hypoxia prevent and reverse ataxia in a murine model of Friedreich’s ataxia

Friedreich’s ataxia (FA) is a devastating, multi-systemic neurodegenerative disease affecting thousands of people worldwide. We previously reported that oxygen is a key environmental variable that can modify FA pathogenesis. In particular, we showed that chronic, continuous normobaric hypoxia (11% F...

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Detalles Bibliográficos
Autores principales: Ast, Tslil, Wang, Hong, Marutani, Eizo, Nagashima, Fumiaki, Malhotra, Rajeev, Ichinose, Fumito, Mootha, Vamsi K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407700/
https://www.ncbi.nlm.nih.gov/pubmed/37260376
http://dx.doi.org/10.1093/hmg/ddad091

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