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Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review

Retroperitoneal liposarcoma (RPLS) is a rare tumor that occurs in the retroperitoneal region and accounts for ~0.2% of all malignant tumor incidence. The present study describes the treatment of a surviving patient with RPLS that recurred five times in 13 years. This case has a long survival time an...

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Autores principales: Qiu, Miao, Lin, De-Rong, Xiong, Zhong-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407717/
https://www.ncbi.nlm.nih.gov/pubmed/37559572
http://dx.doi.org/10.3892/ol.2023.13953
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author Qiu, Miao
Lin, De-Rong
Xiong, Zhong-Kui
author_facet Qiu, Miao
Lin, De-Rong
Xiong, Zhong-Kui
author_sort Qiu, Miao
collection PubMed
description Retroperitoneal liposarcoma (RPLS) is a rare tumor that occurs in the retroperitoneal region and accounts for ~0.2% of all malignant tumor incidence. The present study describes the treatment of a surviving patient with RPLS that recurred five times in 13 years. This case has a long survival time and numerous relapses, which is a rare occurrence. The 40-year-old female patient was admitted to Shaoxing Second Hospital (Shaoxing, China) with an abdominal mass. Abdominal computed tomography (CT) scan revealed multiple liposarcoma recurrences in the abdominal, pelvic and retroperitoneal areas. As the diagnosis of RPLS was the fifth recurrence, cytoreductive surgery was performed and post-operative pathology suggested mixed liposarcoma. The patient underwent six cycles of doxorubicin and ifosfamide regimen chemotherapy and targeted therapy with anlotinib following surgery; no evidence of disease progression was found on abdominal CT scan during follow-up. The present study also reviewed the literature in terms of the clinical diagnosis, treatment, pathological characteristics and similar cases of liposarcoma with the aim of improving diagnosis and treatment.
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spelling pubmed-104077172023-08-09 Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review Qiu, Miao Lin, De-Rong Xiong, Zhong-Kui Oncol Lett Case Report Retroperitoneal liposarcoma (RPLS) is a rare tumor that occurs in the retroperitoneal region and accounts for ~0.2% of all malignant tumor incidence. The present study describes the treatment of a surviving patient with RPLS that recurred five times in 13 years. This case has a long survival time and numerous relapses, which is a rare occurrence. The 40-year-old female patient was admitted to Shaoxing Second Hospital (Shaoxing, China) with an abdominal mass. Abdominal computed tomography (CT) scan revealed multiple liposarcoma recurrences in the abdominal, pelvic and retroperitoneal areas. As the diagnosis of RPLS was the fifth recurrence, cytoreductive surgery was performed and post-operative pathology suggested mixed liposarcoma. The patient underwent six cycles of doxorubicin and ifosfamide regimen chemotherapy and targeted therapy with anlotinib following surgery; no evidence of disease progression was found on abdominal CT scan during follow-up. The present study also reviewed the literature in terms of the clinical diagnosis, treatment, pathological characteristics and similar cases of liposarcoma with the aim of improving diagnosis and treatment. D.A. Spandidos 2023-07-12 /pmc/articles/PMC10407717/ /pubmed/37559572 http://dx.doi.org/10.3892/ol.2023.13953 Text en Copyright: © Qiu et al. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Case Report
Qiu, Miao
Lin, De-Rong
Xiong, Zhong-Kui
Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title_full Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title_fullStr Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title_full_unstemmed Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title_short Survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: A case report and review
title_sort survival of a patient with five recurrences of retroperitoneal liposarcoma over a period of 13 years: a case report and review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407717/
https://www.ncbi.nlm.nih.gov/pubmed/37559572
http://dx.doi.org/10.3892/ol.2023.13953
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AT xiongzhongkui survivalofapatientwithfiverecurrencesofretroperitonealliposarcomaoveraperiodof13yearsacasereportandreview