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NLRC5 potentiates anti-tumor CD8(+) T cells responses by activating interferon-β in endometrial cancer

OBJECTIVES: NLR family CARD domain containing 5 (NLRC5) could promote major histocompatibility complex class I (MHC-I)-dependent CD8(+) T cell-mediated anticancer immunity. In this study, the immunosurveillance role and underlying mechanisms of NLRC5 in endometrial cancer (EC) were characterized. ME...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Guo, Bao, Chen, Jia-Hua, Liu, Xiao-Jing, Zhang, Jun-Hui, Zhu, Hai-Qing, Wang, Wen-Yan, Tang, Zhen-Hai, Wei, Bing, Cao, Yun-Xia, Zhan, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407819/
https://www.ncbi.nlm.nih.gov/pubmed/37531863
http://dx.doi.org/10.1016/j.tranon.2023.101742