Cargando…

NLRC5 potentiates anti-tumor CD8(+) T cells responses by activating interferon-β in endometrial cancer

OBJECTIVES: NLR family CARD domain containing 5 (NLRC5) could promote major histocompatibility complex class I (MHC-I)-dependent CD8(+) T cell-mediated anticancer immunity. In this study, the immunosurveillance role and underlying mechanisms of NLRC5 in endometrial cancer (EC) were characterized. ME...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Jing, Guo, Bao, Chen, Jia-Hua, Liu, Xiao-Jing, Zhang, Jun-Hui, Zhu, Hai-Qing, Wang, Wen-Yan, Tang, Zhen-Hai, Wei, Bing, Cao, Yun-Xia, Zhan, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407819/ https://www.ncbi.nlm.nih.gov/pubmed/37531863 http://dx.doi.org/10.1016/j.tranon.2023.101742

Ejemplares similares

METTL3 facilitates immunosurveillance by inhibiting YTHDF2-mediated NLRC5 mRNA degradation in endometrial cancer
por: Zhan, Lei, et al.
Publicado: (2023)

NLRC5 Might Promote Endometrial Cancer Progression by Inducing PD-L1 Expression
por: Zhu, Su-ding, et al.
Publicado: (2022)

NLRC5 promotes cell migration and invasion by activating the PI3K/AKT signaling pathway in endometrial cancer
por: Fan, Yijun, et al.
Publicado: (2020)

NLRC5 Inhibits Inflammation of Secretory Phase Ectopic Endometrial Stromal Cells by Up-Regulating Autophagy in Ovarian Endometriosis
por: He, Runhua, et al.
Publicado: (2020)

Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
por: Szymczak, Florian, et al.
Publicado: (2022)

Emerging Roles for NLRC5 in Immune Diseases
por: Wang, Jie-quan, et al.
Publicado: (2019)

NLRC5 elicits antitumor immunity by enhancing processing and presentation of tumor antigens to CD8(+) T lymphocytes
por: Rodriguez, Galaxia M., et al.
Publicado: (2016)

NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8(+) T cell responses
por: Souza, Camila O.S., et al.
Publicado: (2021)

The NLRC4 inflammasome requires IRF8-dependent production of NAIPs
por: Lee, Ein, et al.
Publicado: (2018)

Anti interferon-gamma (IFNγ) monoclonal antibody treatment in a patient carrying an NLRC4 mutation and severe hemophagocytic lymphohistiocytosis
por: Bracaglia, C, et al.
Publicado: (2015)

Associations between NLRC4 Gene Polymorphisms and Autoimmune Thyroid Disease
por: Liu, Xuerong, et al.
Publicado: (2020)

Brd4 regulates NLRC4 inflammasome activation by facilitating IRF8-mediated transcription of Naips
por: Dong, Xingchen, et al.
Publicado: (2021)

Macrophage-Specific NLRC5 Protects From Cardiac Remodeling Through Interaction With HSPA8
por: Yu, Qing, et al.
Publicado: (2023)

Roles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseases
por: Correa, Ricardo G., et al.
Publicado: (2012)

Interferon-α-induced CD100 on naïve CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction
por: Li, Bing Jie, et al.
Publicado: (2017)

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy
por: Yuan, Fang, et al.
Publicado: (2016)

NLRC5, at the Heart of Antigen Presentation
por: Neerincx, Andreas, et al.
Publicado: (2013)

NLRC3 negatively regulates CD4(+) T cells and impacts protective immunity during Mycobacterium tuberculosis infection
por: Hu, Shengfeng, et al.
Publicado: (2018)

The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis
por: Wang, Luo-Yi, et al.
Publicado: (2019)

The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats
por: Gan, Hui, et al.
Publicado: (2021)

LDL-induced NLRC3 inflammasome activation in cardiac fibroblasts contributes to cardiomyocytic dysfunction
por: Wang, Peng, et al.
Publicado: (2021)

Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation
por: Sasaki, Yuki, et al.
Publicado: (2020)

NLRP3, NLRC4 and NLRC5 Gene Polymorphisms Associate with Susceptibility of Pulmonary Aspergillosis in Non-Neutropenic Patients
por: Zhong, Jinjin, et al.
Publicado: (2022)

Effect of NLRC5 on activation and reversion of hepatic stellate cells by regulating the nuclear factor-κB signaling pathway
por: Zhang, Yan-Zhen, et al.
Publicado: (2019)

NLRC3: A Novel Noninvasive Biomarker for Pulmonary Hypertension Diagnosis
por: Zha, Li-huang, et al.
Publicado: (2018)

Immune disorder in endometrial cancer: Immunosuppressive microenvironment, mechanisms of immune evasion and immunotherapy
por: Zhan, Lei, et al.
Publicado: (2020)

ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages
por: Lee, Bettina L., et al.
Publicado: (2018)

Serum levels of NLRC4 and MCP-2/CCL8 in patients with active Crohn’s disease
por: Irak, Kader, et al.
Publicado: (2021)

A Study of NLRC4 in Patients with Leprosy
por: Batta, Salma Mosaad, et al.
Publicado: (2023)

High Expression of NLRC5 Is Associated with Prognosis of Gastric Cancer
por: Li, Yuemei, et al.
Publicado: (2018)

Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity
por: Zebertavage, Lauren K., et al.
Publicado: (2020)

NLRC4-mediated activation of CD1c(+) DC contributes to perpetuation of synovitis in rheumatoid arthritis
por: Delgado-Arévalo, Cristina, et al.
Publicado: (2022)

NAIP/NLRC4 inflammasome activation in MRP8(+) cells is sufficient to cause systemic inflammatory disease
por: Nichols, Randilea D., et al.
Publicado: (2017)

LRRK2 promotes the activation of NLRC4 inflammasome during Salmonella Typhimurium infection
por: Liu, Weiwei, et al.
Publicado: (2017)

Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression
por: Yu, Shui-Xing, et al.
Publicado: (2015)

Pseudomonas aeruginosa Induces Interferon-β Production to Promote Intracellular Survival
por: Yang, Ling, et al.
Publicado: (2022)

Emerging Concepts about NAIP/NLRC4 Inflammasomes
por: Lage, Silvia Lucena, et al.
Publicado: (2014)

NAIP–NLRC4-deficient mice are susceptible to shigellosis
por: Mitchell, Patrick S, et al.
Publicado: (2020)

Advances in Understanding Activation and Function of the NLRC4 Inflammasome
por: Sundaram, Balamurugan, et al.
Publicado: (2021)

NLRC4 Inflammasome-Mediated Regulation of Eosinophilic Functions
por: Akkaya, Ilgin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_76a66ak2kgi7jb25ga1pc26ap2