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Synthesis and Conformational Analysis of Hydantoin-Based Universal Peptidomimetics

[Image: see text] The synthesis of a collection of enantiomerically pure, systematically substituted hydantoins as structural privileged universal mimetic scaffolds is presented. It relies on a chemoselective condensation/cyclization domino process between isocyanates of quaternary or unsubstituted...

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Detalles Bibliográficos
Autores principales: Caramiello, Alessio M., Bellucci, Maria Cristina, Cristina, Gaetano, Castellano, Carlo, Meneghetti, Fiorella, Mori, Matteo, Secundo, Francesco, Viani, Fiorenza, Sacchetti, Alessandro, Volonterio, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407853/
https://www.ncbi.nlm.nih.gov/pubmed/36226862
http://dx.doi.org/10.1021/acs.joc.2c01903