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Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature
INTRODUCTION: Testicular cancer is the most frequent solid tumor in young people. Most germ cell tumors of the testis, with the exception of vitelline tumors and teratomas in children, and spermatocytic seminoma in the elderly, derive from a common precursor. This precursor, initially described as c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407882/ https://www.ncbi.nlm.nih.gov/pubmed/37542883 http://dx.doi.org/10.1016/j.ijscr.2023.108609 |
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author | Jdaini, Ahmed El Moudane, Anouar El Farhaoui, Hammou Miry, Nadir Bennani, Amal Barki, Ali |
author_facet | Jdaini, Ahmed El Moudane, Anouar El Farhaoui, Hammou Miry, Nadir Bennani, Amal Barki, Ali |
author_sort | Jdaini, Ahmed |
collection | PubMed |
description | INTRODUCTION: Testicular cancer is the most frequent solid tumor in young people. Most germ cell tumors of the testis, with the exception of vitelline tumors and teratomas in children, and spermatocytic seminoma in the elderly, derive from a common precursor. This precursor, initially described as carcinoma in situ (CIS), is now referred to as intratubular Germinal Cell Neoplasia (ITGCN). CASE PRESENTATION: We report the case of a 37-year-old man with intratubular Germinal Cell Neoplasia (ITGCN) on a testis already treated for cryptorchidism in a context of infertility. We proposed active surveillance, but the patient preferred radiotherapy. DISCUSSION: The origin of ITGCN is still not fully understood. The detection of ITGN is often incidental since it typically does not present with noticeable symptoms, and clinical examination may appear normal. The standard treatment for ITGCN is scrotal radiotherapy. CONCLUSION: The standard treatment for ITGCN is scrotal radiotherapy. However, for patients who desire to preserve fertility, regular observation may be considered as an alternative. |
format | Online Article Text |
id | pubmed-10407882 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-104078822023-08-09 Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature Jdaini, Ahmed El Moudane, Anouar El Farhaoui, Hammou Miry, Nadir Bennani, Amal Barki, Ali Int J Surg Case Rep Case Report INTRODUCTION: Testicular cancer is the most frequent solid tumor in young people. Most germ cell tumors of the testis, with the exception of vitelline tumors and teratomas in children, and spermatocytic seminoma in the elderly, derive from a common precursor. This precursor, initially described as carcinoma in situ (CIS), is now referred to as intratubular Germinal Cell Neoplasia (ITGCN). CASE PRESENTATION: We report the case of a 37-year-old man with intratubular Germinal Cell Neoplasia (ITGCN) on a testis already treated for cryptorchidism in a context of infertility. We proposed active surveillance, but the patient preferred radiotherapy. DISCUSSION: The origin of ITGCN is still not fully understood. The detection of ITGN is often incidental since it typically does not present with noticeable symptoms, and clinical examination may appear normal. The standard treatment for ITGCN is scrotal radiotherapy. CONCLUSION: The standard treatment for ITGCN is scrotal radiotherapy. However, for patients who desire to preserve fertility, regular observation may be considered as an alternative. Elsevier 2023-08-02 /pmc/articles/PMC10407882/ /pubmed/37542883 http://dx.doi.org/10.1016/j.ijscr.2023.108609 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Jdaini, Ahmed El Moudane, Anouar El Farhaoui, Hammou Miry, Nadir Bennani, Amal Barki, Ali Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title | Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title_full | Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title_fullStr | Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title_full_unstemmed | Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title_short | Infertility revealing intratubular germinal cell neoplasia of the testis: Case report and review of the literature |
title_sort | infertility revealing intratubular germinal cell neoplasia of the testis: case report and review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407882/ https://www.ncbi.nlm.nih.gov/pubmed/37542883 http://dx.doi.org/10.1016/j.ijscr.2023.108609 |
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