Cargando…

Programmable Deuteration of Indoles via Reverse Deuterium Exchange

[Image: see text] Methods for selective deuterium incorporation into drug-like molecules have become extremely valuable due to the commercial, mechanistic, and biological importance of deuterated compounds. Herein, we report a programmable labeling platform that allows access to C2, C3, or C2- and C...

Descripción completa

Detalles Bibliográficos
Autores principales: Fitzgerald, Liam S., McNulty, Rachael L., Greener, Andrew, O’Duill, Miriam L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407927/
https://www.ncbi.nlm.nih.gov/pubmed/37477980
http://dx.doi.org/10.1021/acs.joc.3c00819